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H 2 S METABOLISM Enzymology of H 2 S Production H 2 S is produced from the sulfur-containing metabolites cysteine and homocysteine by the enzymes of the transsulfuration pathway, CBS and CSE (43, 254), and from 3-mercaptopyruvate catalyzed by mercaptopyruvate sulfurtransferase (MST) and thioredoxin (170, 250) (Figure 1)

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