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Metformin reduces adenoma formation and aberrant crypt foci formation in mouse models by inhibiting the mitochondrial electron transport chain complex 1 and by activating AMP-activated protein kinase signaling (157, 158)
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[DOI] [Google Scholar] 147.Laurano R., Boffito M., Torchio A., Cassino C., Chiono V., Ciardelli G
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