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LPO and Aβ deposition In the early stages of AD, damage to the mitochondria leads to an accumulation of intracellular ROS, which in turn causes mitochondrial dysfunction (Di Meo et al., 2016) and promotes the deposition of Aβ (Swerdlow et al., 2014)

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1113 Made in China Manufactured for: Dynarex Corporation Orangeburg, NY 10962 www.dynarex.com Revised: 11/2019 PRINCIPAL DISPLAY PANEL: B-12 Compliance Injection Kit NDC 49836-527-01 RX-Only B-12 Compliance Injection Kit Kit Contains: 1 Cyanocobalamin Injection, USP 1,000 mcg/mL (1 mL) 1 Sterile Isopropyl Alcohol 70% Prep Pad 1 Pair Nitrile Powder Free sterile Gloves (Size 7.5) 1 Sterile Towel Drape 1 Sterile Adhesive Bandage 1 Dose Needles and Syringes Not Included B-12 Compliance Injection Kit DISTRIBUTED BY: SCHMIGS HAUPPAUGE, NY 11788 NDC 49836-527-01 MANUFACTURED BY: Rx Pharma Pack HAUPPAUGE, NY 11788 Questions/Comments 1-844-632-7898 Kit Contents: Cyanocobalamin Injection, USP 1,000 mcg/mL* (Manufactured by American Regent) Each mL contains: benzyl alcohol 1.5%