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63 Furthermore, BCAT 1 is selectively upregulated in isocitrate dehydrogenase (IDH) wild-type (WT) GBM, and α-ketoglutarate (α-KG) mediates cell death in BCAT 1-deficient IDH WT GBM
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It is based on the ability of LOOH to oxidize ferrous iron in the presence of xylenol orange, leading to the formation of a colored iron–xylenol-orange complex, which is measured spectrophotometrically [90]
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