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Future investigations could integrate single-cell spatial transcriptomics with epigenetic profiling to resolve tissue-specific stress adaptation mechanisms and provide new strategies for breeding crops for Cd tolerance
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Berberine, on the other hand, triggers cell cycle arrest in the G0/G1 or G2/M phases by downregulating proteins such as Cyclin D1 and Cyclin E and upregulating p21, preventing cancer cells from entering the proliferation and division phases (88)
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