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labial melanotic macule histology Mucosal Oral mucosa
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G protein-coupled receptor kinase (GRK) phosphorylation of these regions in agonist-occupied or constitutively active receptor conformations enhances βarr binding, hindering G protein coupling and leading to receptor desensitization, clathrin-mediated endocytosis, and endosomal trafficking of the βarr-coupled receptor [5]
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